TLR9- cluster of differentiation 289
Toll-like receptor 9 (TLR9) often known as CD289 (cluster of differentiation 289), is a member of the Toll-like receptor family that recognizes pathogen-associated molecular pattern.
TLR8- cluster of differentiation 288
Toll-like receptor 8 (TLR8) often designated as CD288 (cluster of differentiation 288) is a member of evolutionarily conserved Toll-like receptor family which are critical parts of the evolutionarily conserved innate immune system.
TLR7- cluster of differentiation 287
Toll-like receptor 7 (TLR7), is an immune gene possessed by humans, other mammals and additionally in avian species playing a significant role in initiating antiviral immune responses.
TLR6- cluster of differentiation 286
Toll-like receptor 6 (TLR6) often designated as CD286 (cluster of differentiation 286), is a member of the Toll-like receptor family, a highly conserved series of ancient innate immune pattern recognition receptors.
TLR5- cluster of differentiation 285
Toll-like receptor 5 (TLR5), a member of the evolutionarily conserved Toll-like receptor family, has evolved to permit mammals specifically to detect flagellated bacterial pathogens.
TLR4- cluster of differentiation 284
Toll-like receptor 4 (TLR4) often designated as CD284 (cluster of differentiation 284) is a class I transmembrane receptor belonging to the large homologous family of Toll like receptors.
TLR3- cluster of differentiation 283
Toll-like receptor 3 (TLR3) often designated as CD283 (cluster of differentiation 283) is a type I transmembrane receptor protein. It belongs to a family of evolutionary conserved innate immune recognition molecules and recognizes double-stranded RNA, a molecular pattern associated with viral infections.
TLR2- cluster of differentiation 282
Toll-like receptor 2 (TLR2), often designated as CD282 (cluster of differentiation 282) is a type I transmembrane protein belonging to the large homologous family of Toll like receptors.
TLR10- cluster of differentiation 290
Toll-like receptor 10 (TLR10) often known as CD290 (cluster of differentiation 290), is the most recently identified human homolog of the Drosophila TOLL protein. Human TLR10 is an orphan member of the Toll-like receptor family that recognizes pathogen-associated molecular pattern.
TLR1- cluster of differentiation 281
Toll-like receptor 1 (TLR1) often designated as CD281 (cluster of differentiation 281), a member of the Toll-like receptor family recognizes pathogen-associated molecular pattern with specificity for gram-positive bacteria. TLR1 is a 786-residue type I transmembrane protein with a 581-amino acid leucine-rich extracellular domain (ECD), a 23-amino acid transmembrane domain
Stem Cell Factor (SCF)- The c-kit ligand
Hematopoiesis is governed by a number of cytokines that promote the survival, proliferation, and differentiation of hematopoietic stem cells and progenitor cells. Stem cell factor (SCF; also known as kit ligand, mast cell growth factor, or steel factor) is a hematopoietic cytokine that triggers its biologic effects by binding to its receptor, c-kit.
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IMGENEX has now p73 phosphospecific antibody
The p53 family member, p73, also known as tumor protein 73 (TP73) has been recently identified as a structural and functional homolog of the tumor suppressor protein p53. For more details read out the article:
Cytoskeleton-the cellular scaffold
The cytoskeleton is a network of fibers throughout the cell's cytoplasm that helps the cell maintain its shape and gives support to the cell. It is a cellular scaffolding or skeleton contained within the cytoplasm, present in both eukaryotes and prokaryotes. For more details read out the article:
GPR83: A Novel Treg Expressed Cell Surface Marker
GPR83 is a member of the Orphan-A G-Protein coupled receptor family, and has anunknown ligand. It has been previously reported in various regions of the brain, within a subset of T-lymphocytes, and by RT-PCR at low levels in heart, kidney, liver, and otherorgans. For more details read out the article:
New FOXP3Δ2 (Exon 2 Deleted) Specific Antibody
FOXP3 is a master regulator of immune homeostasis expressed specifically in CD4+ CD25+ T regulatory cells controlling their growth, development and function and generally accepted to be expressed in both mouse and human CD4+ CD25+ regulatory T cells. For more details read out the article:
GPR83: A Novel Treg Expressed Cell Surface Marker
GPR83 is a member of the Orphan-A G-Protein coupled receptor family, and has anunknown ligand. It has been previously reported in various regions of the brain, within a subset of T-lymphocytes, and by RT-PCR at low levels in heart, kidney, liver, and otherorgans. For more details read out the article:
Faces of DARPP-32: Master Signaling Mediator in the Brain?
As a major target for dopamine-activated adenylyl cyclase and protein kinase A in the striatum, DARPP-32 plays a central role in regulating the efficacy of dopaminergic neurotransmission and can act either as a phosphatase or kinase inhibitor in a contextually dependent manner. For more detail read out the article:
Epigenetic and Signal Transduction Reagents
IMGENEX offers over 90 Chromatin, DNA Methylation & Repair, and DNA Fragmentation-related antibodies, many of which have been cited in numerous peer-reviewed journals. Find out more details in the following article:
